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MAO is actually a mitochondrial flavin-dependent enzyme that oxidatively deaminates serotonin along with other biogenic and neuroactive amines and it is present while in the liver, intestine and brain of human beings and other mammals. If tryptamines are orally ingested, safety from peripheral degradation by a monoamine oxidase inhibitor (MAOI) may very well be necessary for action. As a result, MAOI normally boosts the pharmacological outcomes of this kind of bioactive amines.
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